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FIG. 2.   Inactivation of CRPV by SDS and comparison with inactivation by N-9. Aliquots of CRPV (10-2 dilution) were mixed with concentrated SDS or concentrated N-9 to a final concentration of 0.05% as described in Materials and Methods. Untreated virus (open circle ) or treated virus (bullet ) was inoculated at two sites each per animal, and papilloma production was measured as the GMD of visible lesions on the indicated days. (a) Comparison of results for 10 SDS-treated and 10 untreated virus inoculation sites. (b) Comparison of 10 N-9-treated and 10 untreated virus inoculation sites. Papilloma production was measured as the average GMD of visible lesions on the indicated days.