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Antimicrob Agents Chemother. 1976 July; 10(1): 164-172
Copyright © 1976 American Society for Microbiology. All Rights Reserved.

Acute Diffuse Interstitial Nephritis Related to Chemotherapy of Tuberculosis

^* Departments of Medicine and Pathology, Veterans Administration Hospital
Vanderbilt University School of Medicine, Nashville, Tennessee 37203

ABSTRACT

Acute renal insufficiency developed in three patients receiving chemotherapy for tuberculosis. It is proposed that acute diffuse interstitial nephritis related to the drugs was responsible for the renal injury. Recovery of renal function was slow and incomplete. Physicians administering chemotherapy to patients with tuberculosis must be aware of the potential nephrotoxicity of the common treatment regimens.