This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Beebe, J. L. Articles by Wlodkowski, T. J. Search for Related Content PubMed PubMed Citation Articles by Beebe, J. L. Articles by Wlodkowski, T. J.

 Previous Article  |  Next Article 

Antimicrob Agents Chemother. 1976 July; 10(1): 179-181
Copyright © 1976 American Society for Microbiology. All Rights Reserved.

Absence of Penicillin-Degrading Enzymes in Penicillin-Resistant Strains of Neisseria gonorrhoeae

Department of Microbiology, Cornell University Medical College, New York, New York 10021

ABSTRACT

Penicillin-resistant and -susceptible strains of Neisseria gonorrhoeae were evaluated for the presence of enzymes capable of degrading penicillin by incubation of [¹⁴C]benzylpenicillin with resting-cell suspensions of N. gonorrhoeae followed by extraction and chromatography of the labeled antibiotic. No degradative activity was observed.

¹ Present address: Clinical Microbiology Service, Columbia-Presbyterian Medical Center, New York, N. Y. 10032.