This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hopfer, R. L. Articles by Gröschel, D. Search for Related Content PubMed PubMed Citation Articles by Hopfer, R. L. Articles by Gröschel, D.

 Previous Article  |  Next Article 

Antimicrob Agents Chemother. 1977 February; 11(2): 277-280
Copyright © 1977 American Society for Microbiology. All Rights Reserved.

Amphotericin B Susceptibility Testing of Yeasts with a Bactec Radiometric System

Department of Laboratory Medicine, The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030

ABSTRACT

The effect of amphotericin B on CO₂ production was studied using a Bactec 225. A radiometric procedure for yeast susceptibility testing that requires 3 h of incubation was developed. A total of 48 yeast isolates was tested in this system and the results were correlated to tube dilution studies. The drug concentration causing at least a 44% decrease in CO₂ production correlated to the tube dilution minimal inhibitory concentration in 85% of isolates tested and was within one tube dilution of the minimal inhibitory concentration in over 95% of yeasts tested.

This article has been cited by other articles:

• Rath, P.-M., Freise, J. M., Ansorg, R. (2002). Susceptibility testing of Aspergillus spp. by means of an automated blood culture system. J Antimicrob Chemother 50: 115-117 [Abstract] [Full Text]