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Antimicrob Agents Chemother. 1977 February; 11(2): 359-361
Copyright © 1977 American Society for Microbiology. All Rights Reserved.

Hemagglutination Inhibition Assay for Gentamicin

Department of Medicine, Toronto General Hospital, Toronto, Ontario, Canada
Technam, Inc., Park Forest South, Illinois 60466
Governors State University, Park Forest South, Illinois 60466

ABSTRACT

A rapid and simple hemagglutination inhibition test for measuring gentamicin concentrations in serum has been developed. Correlation coefficients for this assay with the radioimmunoassay and microbiological assay were r = 710 and r = 0.864, respectively. Measurements of gentamicin levels in serum by the three methods showed no statistically significant differences. The hemagglutination inhibition assay is fast, reliable, and relatively inexpensive, and should prove valuable for laboratory use.