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Antimicrob Agents Chemother. 1977 March; 11(3): 411-414
Copyright © 1977 American Society for Microbiology. All Rights Reserved.

Antibiotic Metabolites from a Marine Pseudomonad

Stephen J. Wratten, Margaret S. Wolfe, Raymond J. Andersen and D. John Faulkner

Scripps Institution of Oceanography, La Jolla, California 92093

ABSTRACT

An antibiotic-producing pseudomonad was isolated from a seawater sample from a La Jolla, Calif., tidepool. The pseudomonad produces two novel antibacterial compounds, 2-n-pentyl-4-quinolinol and 2-n-heptyl-4-quinolinol. It also synthesizes indole-3-carboxaldehyde, 6-bromoindole-3-carboxaldehyde, and the known antibiotic p-hydroxybenzaldehyde. Each of these compounds was identified by analysis of spectral data, and the structures were confirmed by synthesis or comparison with authentic samples.


Antimicrob Agents Chemother. 1977 March; 11(3): 411-414
Copyright © 1977 American Society for Microbiology. All Rights Reserved.




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