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Antimicrob Agents Chemother. 1977 April; 11(4): 577-579
Copyright © 1977 American Society for Microbiology. All Rights Reserved.

In Vitro Activity of Cinoxacin, Ampicillin, and Chloramphenicol Against Shigella and Nontyphoid Salmonella

Sheba Medical Center, Tel-Aviv University, Sackler School of Medicine, Tel-Hashomer, Israel

ABSTRACT

The in vitro antibacterial activity of cinoxacin was compared with that of ampicillin and chloramphenicol against 26 strains of nontyphoid Salmonella and 44 strains of Shigella. Cinoxacin was found to have a lower minimal inhibitory concentration than ampicillin and chloramphenicol against all Salmonella and Shigella sonnei strains. Cinoxacin had minimal inhibitory concentrations similar to those of chloramphenicol but lower than those of ampicillin against Shigella flexneri and S. boydii strains.