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Antimicrob Agents Chemother. 1977 April; 11(4): 619-624
Copyright © 1977 American Society for Microbiology. All Rights Reserved.

Plasmid-Mediated Aminoglycoside Phosphotransferase of Broad Substrate Range That Phosphorylates Amikacin

Patrice Courvalin and Julian Davies

Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706

ABSTRACT

A plasmid-mediated aminoglycoside phosphotransferase that phosphorylates amikacin has been detected in clinical isolates of Staphylococcus aureus. This enzyme does not confer detectable amikacin resistance to the strains.

Antimicrob Agents Chemother. 1977 April; 11(4): 619-624
Copyright © 1977 American Society for Microbiology. All Rights Reserved.





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Copyright © 1977 by the American Society for Microbiology. All rights reserved.