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Antimicrob Agents Chemother. 1977 July; 12(1): 1-3
Copyright © 1977 American Society for Microbiology. All Rights Reserved.

Inducible High Resistance to Colistin in Proteus Strains

Shoji Shimizu, Shizuko Iyobe and Susumu Mitsuhashi

Department of Microbiology, School of Medicine, Gunma University, Maebashi, Japan

ABSTRACT

Wild-type Proteus strains are usually resistant to colistin. We have observed an increase in the level of colistin resistance in four clinical isolates of P. vulgaris, P. morganii, and P. rettgeri by prior treatment with subinhibitory concentrations of the drug. The enhanced resistance in these strains was lost after cultivating them in colistin-free medium, indicating that the enhanced resistance in the Proteus group is inducible.

Antimicrob Agents Chemother. 1977 July; 12(1): 1-3
Copyright © 1977 American Society for Microbiology. All Rights Reserved.





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