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Antimicrob Agents Chemother. 1977 July; 12(1): 122-123
Copyright © 1977 American Society for Microbiology. All Rights Reserved.

Pharmacokinetic Study of Netilmicin

Burt R. Meyers, Shalom Z. Hirschman, Gary Wormser and David Siegel

1 Division of Infectious Diseases, Department of Medicine, Mt. Sinai School of Medicine of the City University of New York, New York, New York 10029

ABSTRACT

Netilmicin at a dose of 2 mg/kg was infused intravenously into 10 healthy volunteers. A peak serum concentration of 16.56 µg/ml was obtained at the end of the infusion. Thirty-nine percent of the infused dose was excreted in the urine during the first 8 h after infusion. The pharmacokinetic parameters of netilmicin were derived by analyzing the elimination data according to a two-compartment model.

Antimicrob Agents Chemother. 1977 July; 12(1): 122-123
Copyright © 1977 American Society for Microbiology. All Rights Reserved.





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Clin. Vaccine Immunol. Clin. Microbiol. Rev.
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Copyright © 1977 by the American Society for Microbiology. All rights reserved.