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Antimicrob Agents Chemother. 1977 August; 12(2): 288-289
Copyright © 1977 American Society for Microbiology. All Rights Reserved.

Correlation of Netilmicin Agar Dilution and Disk Diffusion Susceptibilities

Donald A. Goldmann*, Georgia Ph. Syriopoulou and Anne Markley Semple

* Bacteriology Laboratory and Division of Infectious Diseases, Children's Hospital Medical Center, Boston, Massachusetts 02115
Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115

ABSTRACT

A study of 283 isolates of gram-negative bacilli revealed a good correlation (r = –0.74) between disk diffusion zones of inhibition and agar dilution minimal inhibitory concentrations. Regression analysis suggested that strains with zone sizes 11 mm should be considered resistant, but 34 of 45 strains resistant by minimal inhibitory concentration (including 27 strains of Pseudomonas aeruginosa) would have been called susceptible using this break point.


Antimicrob Agents Chemother. 1977 August; 12(2): 288-289
Copyright © 1977 American Society for Microbiology. All Rights Reserved.