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Antimicrob Agents Chemother. 1978 October; 14(4): 636-638
Copyright © 1978 American Society for Microbiology. All Rights Reserved.

Artifactual Depression of Serum Glutamic Oxaloacetic Transaminase by Metronidazole

J. Peter Rissing, Cheryl Newman and William L. Moore Jr.

Veterans Administration Hospital and Department of Medicine, Medical College of Georgia, Augusta, Georgia 30904

ABSTRACT

Eighteen patients developed abnormally low serum glutamic oxaloacetic transaminase values during metronidazole therapy. Metronidazole absorbs at 340 nm, simulating reduced nicotinamide adenine dinucleotide, which is the final colorimetric product of the serum glutamic oxaloacetic transaminase assay.

Antimicrob Agents Chemother. 1978 October; 14(4): 636-638
Copyright © 1978 American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Lambert, J. R., Thomas, S. M. (1985). Metronidazole Prevention of Serum Liver Enzyme Abnormalities during Total Parenteral Nutrition. JPEN J Parenter Enteral Nutr 9: 501-503 [Abstract]  


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