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Antimicrob Agents Chemother. 1979 October; 16(4): 525-527

Erythromycin and clindamycin resistance in Corynebacterium diphtheriae from skin lesions.

M B Coyle, B H Minshew, J A Bland and P C Hsu

ABSTRACT

Erythromycin- and clindamycin-resistant Corynebacterium diphtheriae isolates were recovered from skin lesions. Resistance to erythromycin and clindamycin was induced by a subinhibitory concentration (0.03 microgram/ml) of erythromycin. Clindamycin (0.07 microgram/ml) was a more effective inducer of its own resistance than of erythromycin resistance. Erythromycin-inducible cross-resistance to vernamycin B alpha was demonstrated in disk diffusion tests.

Antimicrob Agents Chemother. 1979 October; 16(4): 525-527




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