Antimicrob Agents Chemother. 1980 June; 17(6): 1034-1037
ABSTRACT
The mechanism of the potent virucidal activity of retinol (vitamin A) and retinal (vitamin A aldehyde) was investigated for the interaction of these compounds with a model system enveloped virus, bacteriophage phi 6. The retinoids bind to and inactivate phi 6 without causing large-scale disruption of the virion. Inactivated virions have completely lost the ability to adsorb to host bacteria due to the loss of a viral envelope protein necessary for adsorption.
| Clin. Vaccine Immunol. | Clin. Microbiol. Rev. |
|---|---|
| J. Clin. Microbiol. | ALL ASM JOURNALS |