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Antimicrob Agents Chemother. 1980 June; 17(6): 954-956

In vitro activity of mecillinam against anaerobic bacteria.

G E Steinkraus and L R McCarthy

ABSTRACT

A microtiter broth dilution method was employed to determine the in vitro activity of mecillinam against 201 recent clinical isolates of anaerobic bacteria. Both the anerobic gram-positive and anaerobic gram-negative bacilli displayed a wide range of minimal inhibitory concentrations of mecillinam; most strains were resistant to the antibiotic. The anaerobic cocci exhibited a narrower range of minimal inhibitory concentrations than were observed with other anaerobes, but also exhibited mecillinam resistance. As a single durg, mecillinam does not appear to be an effective antimicrobial agent against anaerobic bacteria.

Antimicrob Agents Chemother. 1980 June; 17(6): 954-956






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