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Antimicrob Agents Chemother. 1982 May; 21(5): 848-851

Comparative in vitro activity of norfloxacin (MK-0366) and ten other oral antimicrobial agents against urinary bacterial isolates.

M Y Khan, R P Gruninger, S M Nelson and R E Klicker

ABSTRACT

The in vitro activity of a new oral antimicrobial agent, norfloxacin (MK-0366), was compared with those of nalidixic acid, nitrofurantoin, co-trimoxazole, trimethoprim, sulfamethoxazole, cinoxacin, tetracycline, ampicillin, carbenicillin, and cephalexin against 628 urinary bacterial isolates. Norfloxacin was the most active antimicrobial agent tested against the gram-negative bacilli. It was less active than a few of the other antimicrobial agents against enterococci and Staphylococcus aureus.


Antimicrob Agents Chemother. 1982 May; 21(5): 848-851




This article has been cited by other articles:

  • WOLFSON, J. S., HOOPER, D. C. (1988). Norfloxacin: A New Targeted Fluoroquinolone Antimicrobial Agent. ANN INTERN MED 108: 238-251 [Abstract]  
  • Stein, G. E., Mummaw, N., Goldstein, E. J. C., Boyko, E. J., Reller, L. B., Kurtz, T. O., Miller, K., Cox, C. E. (1987). A Multicenter Comparative Trial of Three-Day Norfloxacin vs Ten-Day Sulfamethoxazole and Trimethoprim for the Treatment of Uncomplicated Urinary Tract Infections. Arch Intern Med 147: 1760-1762 [Abstract]