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Antimicrob Agents Chemother. 1985 June; 27(6): 982-984

In vitro comparative antimicrobial activity of cefpimizole against clinical isolates from five medical centers.

R N Jones, L W Ayers, T L Gavan, E H Gerlach and H M Sommers

ABSTRACT

Cefpimizole was compared with cefoperazone and cefotaxime against 6,599 clinical bacterial isolates from five medical centers. Cefoperazone and cefotaxime were both more active and provided a greater spectrum of antimicrobial coverage than cefpimizole. Some of the cefpimizole minimum concentrations inhibiting 50% of tested strains were as follows: Citrobacter freundii and Enterobacter cloacae, 16 micrograms/ml; Escherichia coli and Klebsiella pneumoniae, 2.0 micrograms/ml; Proteus mirabilis, 1.0 microgram/ml; Pseudomonas aeruginosa, 16 micrograms/ml; Staphylococcus spp., 32 micrograms/ml; and the enterococci, greater than 32 micrograms/ml.

Antimicrob Agents Chemother. 1985 June; 27(6): 982-984






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