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Antimicrob Agents Chemother. 1985 July; 28(1): 144-145

Effects of elevation of serum cholesterol and administration of amphotericin B complexed to lipoproteins on amphotericin B-induced toxicity in rabbits.

M H Koldin, G S Kobayashi, J Brajtburg and G Medoff

ABSTRACT

Amphotericin B was infused into normal rabbits or rabbits made hypercholesterolemic by diet. There was no difference in amphotericin B-induced toxicity between these two groups. Amphotericin B given in a mixture with human low-density lipoproteins was more toxic than when given without lipoproteins.

Antimicrob Agents Chemother. 1985 July; 28(1): 144-145




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