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Antimicrob Agents Chemother. 1986 December; 30(6): 948-950

In vitro activity of A-56619 (difloxacin), A-56620, and other new quinolone antimicrobial agents against genital pathogens.

L D Liebowitz, J Saunders, G Fehler, R C Ballard and H J Koornhof

ABSTRACT

The in vitro activities of two new carboxyquinolones, A-56619 (difloxacin) and A-56620, were compared with those of ciprofloxacin, norfloxacin, and ofloxacin against genital tract pathogens. All the quinolones were highly active against Neisseria gonorrhoeae. A-56619 had the lowest MICs against Chlamydia trachomatis (MIC range, 0.125 to 0.25 micrograms/ml) and Haemophilus ducreyi (MIC for 90% of isolates tested, 0.1 micrograms/ml).

Antimicrob Agents Chemother. 1986 December; 30(6): 948-950




This article has been cited by other articles:

  • WOLFSON, J. S., HOOPER, D. C. (1988). Norfloxacin: A New Targeted Fluoroquinolone Antimicrobial Agent. ANN INTERN MED 108: 238-251 [Abstract]  


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