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Antimicrob Agents Chemother. 1987 April; 31(4): 650-652

In vitro activity of paldimycin (U-70138F) against gram-positive bacteria isolated from patients with cancer.

K V Rolston, B LeBlanc, D H Ho and G P Bodey

ABSTRACT

The in vitro activity of paldimycin, a novel antimicrobial agent, was compared with that of vancomycin against 306 gram-positive isolates (representing 12 bacterial species) obtained from patients with cancer. Paldimycin had lower MICs for 90% of isolates than vancomycin did against most isolates tested. Its activity, however, was medium and pH dependent, being greatest in Nutrient broth at a pH of 6.8.


Antimicrob Agents Chemother. 1987 April; 31(4): 650-652







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