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Antimicrob Agents Chemother. 1987 July; 31(7): 1143-1146

Environmental exposure of primary care personnel to ribavirin aerosol when supervising treatment of infants with respiratory syncytial virus infections.

W J Rodriguez, R H Bui, J D Connor, H W Kim, C D Brandt, R H Parrott, B Burch and J Mace

Children's Hospital National Medical Center, George Washington University School of Medicine and the Health Sciences, Washington, D.C. 20010.

ABSTRACT

The potential exposure to ribavirin aerosol in the environment was assessed in nurses caring for infants and children with severe lower respiratory tract infections due to respiratory syncytial virus. Ribavirin aerosol was administered via a ventilator, oxygen tent, or oxygen hood. Participants worked directly with infants receiving ribavirin for 20.0 to 35.0 h over a 3-day period. No toxic or adverse effects of ribavirin aerosol were observed in any of the 19 nurses studied, and ribavirin was not detected in erythrocytes, plasma, or urine collected after the potential exposure period.

Antimicrob Agents Chemother. 1987 July; 31(7): 1143-1146




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  • Balfour, H. H. Jr, Englund, J. A. (1989). Antiviral Drugs in Pediatrics. Arch Pediatr Adolesc Med 143: 1307-1316 [Abstract]  
  • (1988). Assessing Exposures of Health-Care Personnel to Aerosols of Ribavirin--California. JAMA 260: 1844-1845  
  • Outwater, K. M., Meissner, H. C., Peterson, M. B. (1988). Ribavirin Administration to Infants Receiving Mechanical Ventilation. Arch Pediatr Adolesc Med 142: 512-515 [Abstract]  


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