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Antimicrob Agents Chemother. 1988 September; 32(9): 1456-1457

Antibacterial effect of etoposide in vitro.

W Calame, R van der Waals, N Douwes-Idema, H Mattie and R van Furth

Department of Infectious Diseases, University Hospital, Leiden, The Netherlands.

ABSTRACT

Etoposide, an antitumor drug, had an effect in vitro against all strains of gram-positive bacteria studied but not against three gram-negative bacteria. The MICs ranged between 6.2 and 50 micrograms/ml. In short-term-growth experiments, etoposide had a bactericidal efficacy that was 10 to 50 times lower than that of cloxacillin.


Antimicrob Agents Chemother. 1988 September; 32(9): 1456-1457







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