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Antimicrob Agents Chemother. 1973 July; 4(1): 69-71
Copyright © 1973 American Society for Microbiology. All Rights Reserved.

Effect of Oral Tetracycline on the Occurrence of Tetracycline-Resistant Strains of Escherichia coli in the Intestinal Tract of Humans

Dwight C. Hirsh, Glenna C. Burton and Donald C. Blenden

1 Department of Veterinary Microbiology, School of Veterinary Medicine, University of Missouri, Columbia, Missouri 65201

ABSTRACT

Serial samples of feces from normal human subjects were analyzed for tetracycline-resistant strains of Escherichia coli. Subjects were found to be excreting tetracycline-resistant strains in amounts fluctuating with time. Ingestion of tetracycline increased both the number of individuals excreting tetracycline-resistant strains of E. coli and the proportion of the total E. coli isolates resistant to the antibiotic.


Antimicrob Agents Chemother. 1973 July; 4(1): 69-71
Copyright © 1973 American Society for Microbiology. All Rights Reserved.