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Antimicrob. Agents Chemother., Oct 1997, 2317-2319, Vol 41, No. 10
Copyright © 1997 by the American Society for Microbiology. All rights reserved.

Pyronaridine for treatment of Plasmodium ovale and Plasmodium malariae infections

P Ringwald, J Bickii, A Same-Ekobo and LK Basco
Institut Francais de Recherche Scientifique pour le Developpement en Cooperation (ORSTOM), Organisation de Coordination pour la lutte contre les Endemies en Afrique Centrale, Yaounde, Cameroon.

The clinical efficacy of oral pyronaridine was assessed in 22 symptomatic Cameroonian patients infected with Plasmodium ovale or Plasmodium malariae. All patients were cured on or before day 4. In vitro drug assays confirmed the sensitivity of P. ovale and P. malariae isolates to chloroquine and pyronaridine.

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