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Antimicrobial Agents and Chemotherapy, 05 1997, 1137-1139, Vol 41, No. 5
Copyright © 1997 by the American Society for Microbiology. All rights reserved.

Interpretive criteria for testing susceptibility of staphylococci to mupirocin

JE Finlay, LA Miller and JA Poupard
SmithKline Beecham Pharmaceuticals, Collegeville, Pennsylvania 19426, USA.

To determine appropriate mupirocin susceptibility testing interpretive criteria, 177 staphylococci were tested by agar dilution, disk diffusion, and E test. E test was found to be a reliable method for determining susceptibility of staphylococci to mupirocin. The agar dilution and disk diffusion results were plotted on a scattergram, and error rates were calculated. No errors were found with susceptibility breakpoints of > or = 4 microg/ml (MIC) and > or = 14 mm (zone diameter).


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