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Antimicrobial Agents and Chemotherapy, October 1998, p. 2762-2764, Vol. 42, No. 10
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

In Vitro Susceptibilities of Chlamydia pneumoniae Strains Recovered from Atherosclerotic Coronary Arteries

Jens Gieffers,* Werner Solbach, and Matthias Maass

Institute of Medical Microbiology and Hygiene, Medical University of Lübeck, D-23538 Lübeck, Germany

Received 20 March 1998/Returned for modification 14 July 1998/Accepted 24 July 1998

Chlamydia pneumoniae strains have been recovered from arteriosclerotic coronary arteries, but their antibiotic susceptibility profiles have not yet been examined. We report in vitro susceptibility data for five cardiovascular C. pneumoniae isolates. These strains did not differ significantly from respiratory strains in their patterns of susceptibility to azithromycin, erythromycin, roxithromycin, ofloxacin, doxycycline, rifampin, and penicillin G. Roxithromycin was the most active macrolide, and rifampin was the most effective drug overall.

* Corresponding author. Mailing address: Institute of Medical Microbiology and Hygiene, Medical University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany. Phone: 49 (451) 500-2818. Fax: 49 (451) 500-2808. E-mail: gieffers{at}hygiene.mu-luebeck.de.

Antimicrobial Agents and Chemotherapy, October 1998, p. 2762-2764, Vol. 42, No. 10
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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