This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ruiz, J.
Right arrow Articles by Fenoll, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ruiz, J.
Right arrow Articles by Fenoll, A.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, October 1998, p. 2768-2769, Vol. 42, No. 10
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Description of Two New Isolates of Streptococcus pneumoniae in Spain That Are Highly Resistant to Cefotaxime

Joaquín Ruiz,1,* Marco Sempere,2 Encarnación Simarro,1 and Asunción Fenoll3

Sección de Microbiología, Hospital Universitario Virgen de la Arrixaca, El Palmar 30120, Murcia,1 Laboratorio de Análisis Clínicos, Hospital Costa del Sol, Marbella, Málaga,2 and Centro Nacional de Microbiología, Majadahonda 28220, Madrid,3 Spain

Received 23 February 1998/Returned for modification 22 June 1998/Accepted 7 August 1998

Two strains of Streptococcus pneumoniae isolated from sputum and bronchoalveolar samples with high-level resistance to cefotaxime (MIC = 8 to 16 µg/ml) are described. One of them, belonging to serogroup 19, was also highly resistant to penicillin (MIC = 16 µg/ml), while the other, of serogroup 14, was intermediate in its resistance to penicillin (MIC = 0.25 µg/ml). To our knowledge, these are the first two strains to be isolated in Spain with such high levels of resistance to cefotaxime.

* Corresponding author. Mailing address: Jaime I 1, 3° izq., 30008, Murcia, Spain. Phone: 34-68-237099. Fax: 34-68-369678. E-mail: micro{at}isid.es.

Antimicrobial Agents and Chemotherapy, October 1998, p. 2768-2769, Vol. 42, No. 10
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Soriano, F., Cafini, F., Aguilar, L., Tarrago, D., Alou, L., Gimenez, M.-J., Gracia, M., Ponte, M.-C., Leu, D., Pana, M., Letowska, I., Fenoll, A. (2008). Breakthrough in penicillin resistance? Streptococcus pneumoniae isolates with penicillin/cefotaxime MICs of 16 mg/L and their genotypic and geographical relatedness. J Antimicrob Chemother 62: 1234-1240 [Abstract] [Full Text]  
  • Ribes, S., Taberner, F., Domenech, A., Cabellos, C., Tubau, F., Linares, J., Viladrich, P. F., Gudiol, F. (2005). Evaluation of ceftriaxone, vancomycin and rifampicin alone and combined in an experimental model of meningitis caused by highly cephalosporin-resistant Streptococcus pneumoniae ATCC 51916. J Antimicrob Chemother 56: 979-982 [Abstract] [Full Text]  
  • Canica, M., Dias, R., Louro, D., Carvalho, C., the Multicentre Study Group, (2002). In vitro activity of extended-spectrum cephalosporins against Streptococcus pneumoniae strains with reduced susceptibility to penicillin isolated from patients in Portugal between 1995 and 2000. J Antimicrob Chemother 50: 611-612 [Full Text]  
  • BRETT, M. S. (2001). Emergence of a high-level cefotaxime-resistant Streptococcus pneumoniae strain in New Zealand. J Med Microbiol 50: 173-176 [Abstract] [Full Text]  
  • Luna, V. A., Jernigan, D. B., Tice, A., Kellner, J. D., Roberts, M. C. (2000). A Novel Multiresistant Streptococcus pneumoniae Serogroup 19 Clone from Washington State Identified by Pulsed-Field Gel Electrophoresis and Restriction Fragment Length Patterns. J. Clin. Microbiol. 38: 1575-1580 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»