This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Piccolomini, R.
Right arrow Articles by Di Bonaventura, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Piccolomini, R.
Right arrow Articles by Di Bonaventura, G.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, November 1998, p. 3000-3001, Vol. 42, No. 11
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Bacteriostatic and Bactericidal In Vitro Activities of Clarithromycin and Erythromycin against Periodontopathic Actinobacillus actinomycetemcomitans

R. Piccolomini,* G. Catamo, and G. Di Bonaventura

Department of Biomedical Sciences, Clinical Microbiology Laboratory, "G. D'Annunzio" University, I-66100 Chieti, Italy

Received 16 March 1998/Returned for modification 2 June 1998/Accepted 8 August 1998

The susceptibilities of 87 periodontitis-associated strains of Actinobacillus actinomycetemcomitans to clarithromycin and erythromycin were determined by standard methodology recommended for Haemophilus influenzae. For clarithromycin the MIC at which 90% of the isolates were inhibited was <= 2.0 µg/ml and the minimal bactericidal concentration at which 90% of the strains were killed was <= 4.0 µg/ml, suggesting that it would be a candidate for therapeutic trials in patients with periodontitis.

* Corresponding author. Mailing address: Dipartimento di Scienze Biomediche, Laboratorio di Microbiologia Clinica, Università "G. d'Annunzio," Via dei Vestini, 31, I-66100 Chieti, Italy. Phone: (39) 871-3555283. Fax: (39) 871-3555282. E-mail: r.piccolomini{at}dsb.unich.it.

Antimicrobial Agents and Chemotherapy, November 1998, p. 3000-3001, Vol. 42, No. 11
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Chou, C.-H., Walters, J.D. (2008). Clarithromycin Transport by Gingival Fibroblasts and Epithelial Cells. JDR 87: 777-781 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»