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Antimicrobial Agents and Chemotherapy, November 1998, p. 3009-3011, Vol. 42, No. 11
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Comparison of Ceftriaxone, Amikacin, and Ciprofloxacin in Treatment of Experimental Yersinia enterocolitica O9 Infection in Mice

Maria Jiménez-Valera, Concepción Gonzalez-Torres, Encarnación Moreno, and Alfonso Ruiz-Bravo*

Department of Microbiology, Faculty of Pharmacy, University of Granada, Granada, Spain

Received 28 January 1998/Returned for modification 5 March 1998/Accepted 26 August 1998

Ceftriaxone and ciprofloxacin were effective in the treatment of Yersinia enterocolitica O9 intestinal infection in mice. Amikacin was less effective. The impact of these drugs on indigenous bacteria from the intestinal microbiota was studied.

* Corresponding author. Mailing address: Departamento de Microbiología, Facultad de Farmacia, Universidad de Granada, Granada 18071, Spain. Phone: (58)243870. Fax: (58)246235. E-mail: aruizbr{at}platon.ugr.es.

Antimicrobial Agents and Chemotherapy, November 1998, p. 3009-3011, Vol. 42, No. 11
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.




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