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Antimicrobial Agents and Chemotherapy, December 1998, p. 3293-3295, Vol. 42, No. 12
Department of Urology, Gifu University School
of Medicine, Gifu, Japan
Received 18 June 1998/Returned for modification 13 August
1998/Accepted 9 September 1998
We examined 22 clinical isolates of Staphylococcus
epidermidis to analyze the association of alterations in GyrA and
ParC with fluoroquinolone resistance. The simultaneous presence of GyrA
and ParC alterations was associated with a high level of fluoroquinolone resistance in the clinical isolates of S. epidermidis.
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
Alteration in the GyrA Subunit of DNA Gyrase and the ParC Subunit
of DNA Topoisomerase IV in Quinolone-Resistant Clinical Isolates of
Staphylococcus epidermidis
*
Corresponding author. Mailing address: Department of
Urology, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu
City, Gifu 500-8705, Japan. Phone: 81-58-265-1241. Fax: 81-58-265-9009. E-mail: deguchit{at}cc.gifu-u.ac.jp.
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