Antimicrobial Agents and Chemotherapy, May 1998, p. 1245-1248, Vol. 42, No. 5
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
-Lactamase Family from Stenotrophomonas
maltophilia
Microbiologie Moléculaire et Génie des Protéines, Sciences de la Vie et de la Santé, Pavillon Charles-Eugène Marchand et Faculté de Médecine, Université Laval, Ste-Foy, Québec, Canada G1K 7P4
Received 8 July 1997/Returned for modification 21 October 1997/Accepted 10 February 1998
We have determined the nucleotide sequence of the blaS
gene encoding the carbapenem-hydrolyzing L-1
-lactamase from
Stenotrophomonas maltophilia GN12873. Analysis of the DNA
and deduced amino acid sequences identified a product of 290 amino
acids. Comparisons of the L-1 amino acid sequence with those of other
zinc
-lactamases showed 88.6% identity with the L-1 enzyme from
S. maltophilia IID1275 and less than 20% identity with
other class B metalloenzymes.
This article has been cited by other articles:
| Clin. Vaccine Immunol. | Clin. Microbiol. Rev. |
|---|---|
| J. Clin. Microbiol. | ALL ASM JOURNALS |