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Antimicrobial Agents and Chemotherapy, June 1998, p. 1493-1494, Vol. 42, No. 6
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Different Erythromycin Resistance Mechanisms in Group C and Group G Streptococci

Janne Kataja,1,* Helena Seppälä,1,2 Mikael Skurnik,3 Hannu Sarkkinen,4 and Pentti Huovinen1

Antimicrobial Research Laboratory, National Public Health Institute,1 Department of Ophthalmology, University of Turku,2 and Turku Centre for Biotechnology, University of Turku and Åbo Akademi University,3 Turku, and Central Hospital of Päijät-Häme, Lahti,4 Finland

Received 10 November 1997/Returned for modification 21 January 1998/Accepted 25 March 1998

Different mechanisms of erythromycin resistance predominate in group C and G streptococcus (GCS and GGS, respectively) isolates collected from 1992 to 1995 in Finland. Of the 21 erythromycin-resistant GCS and 32 erythromycin-resistant GGS isolates, 95% had the mefA or mefE drug efflux gene and 94% had the ermTR methylase gene, respectively.

* Corresponding author. Mailing address: Antimicrobial Research Laboratory, National Public Health Institute, P.O. Box 57, 20521 Turku, Finland. Phone: 358-2-2519255. Fax: 358-2-2519254. E-mail: janne.kataja{at}utu.fi.

Antimicrobial Agents and Chemotherapy, June 1998, p. 1493-1494, Vol. 42, No. 6
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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