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Antimicrobial Agents and Chemotherapy, August 1998, p. 2116-2118, Vol. 42, No. 8
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
Tn5706, a Transposon-Like Element from
Pasteurella multocida Mediating Tetracycline
Resistance
Corinna
Kehrenberg,
Christiane
Werckenthin, and
Stefan
Schwarz*
Institut für Tierzucht und
Tierverhalten der Bundesforschungsanstalt für Landwirtschaft
Braunschweig-Völkenrode, 29223 Celle, Germany
Received 9 February 1998/Returned for modification 27 March
1998/Accepted 11 May 1998
The 4,378-bp putative tetracycline resistance transposon
Tn5706 of Pasteurella multocida consists of
an internal tet(H)-tetR resistance gene region which is flanked by almost identical insertion elements, IS1596 and IS1597. Two reading
frames for proteins of 70 and 228 amino acids were detected in each of
these insertion sequence elements. The 228-amino-acid protein revealed
homology to transposase proteins of gram-positive bacteria.
*
Corresponding author. Mailing address: Institut
für Tierzucht und Tierverhalten der Bundesforschungsanstalt
für Landwirtschaft Braunschweig/Völkenrode (FAL),
Dörnbergstr. 25-27, 29223 Celle, Germany. Phone:
49-5141-384673/75. Fax: 49-5141-381849. E-mail: schwarz{at}ktf.fal.de.
Antimicrobial Agents and Chemotherapy, August 1998, p. 2116-2118, Vol. 42, No. 8
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.
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