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Antimicrobial Agents and Chemotherapy, August 1998, p. 2125-2127, Vol. 42, No. 8
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Molecular Characterization of a TEM-21 beta -Lactamase in a Clinical Isolate of Morganella morganii

F. Tessier,1,* C. Arpin,1 A. Allery,2 and C. Quentin1

Laboratoire de Microbiologie, Université de Bordeaux 2,1 and Laboratoire de Bactériologie, Hôpital Pellegrin,2 Bordeaux, France

Received 14 October 1997/Returned for modification 4 February 1998/Accepted 10 May 1998

A clinical isolate of Morganella morganii, with reduced susceptibility to expanded-spectrum cephalosporins and aztreonam, was found to produce an extended-spectrum beta -lactamase with a pI of 6.4. The nucleotide sequence of the encoding gene was that of the gene encoding TEM-21. This is the first molecular characterization of an extended-spectrum beta -lactamase in M. morganii.

* Corresponding author. Mailing address: Laboratoire de Microbiologie, Université de Bordeaux 2, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France. Phone: (33) 5 57 57 10 75. Fax: (33) 5 56 90 90 72. E-mail: Francoise.Tessier{at}bacterio.u-bordeaux2.fr.

Antimicrobial Agents and Chemotherapy, August 1998, p. 2125-2127, Vol. 42, No. 8
0066-4804/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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