This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vila, J.
Right arrow Articles by Gascon, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vila, J.
Right arrow Articles by Gascon, J.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, December 1999, p. 3022-3024, Vol. 43, No. 12
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Antimicrobial Resistance of Diarrheagenic Escherichia coli Isolated from Children under the Age of 5 Years from Ifakara, Tanzania

Jordi Vila,1,* Martha Vargas,1 Climent Casals,1 Honorato Urassa,2 Hassan Mshinda,2 David Schellemberg,2 and Joaquim Gascon1

Departament de Microbiologia, Hospital Clinic, IDIBAPS (Institut d'Investigacions Biomèdiques August Pí i Sunyer), Barcelona 08036, Spain,1 and Ifakara Health Research and Development Centre, National Institute for Medical Research, Ifakara, Tanzania2

Received 15 June 1999/Returned for modification 16 August 1999/Accepted 2 October 1999

Diarrhea caused by multidrug-resistant bacteria is an important public health problem among children in developing countries. The prevalence and antimicrobial susceptibility of diarrheagenic Escherichia coli in 346 children under 5 years of age in Ifakara, Tanzania, were studied. Thirty-eight percent of the cases of diarrhea were due to multiresistant enterotoxigenic E. coli, enteroaggregative E. coli, or enteropathogenic E. coli. Strains of all three E. coli categories showed high-level resistance to ampicillin, tetracycline, co-trimoxazole, and chloramphenicol but were highly susceptible to quinolones. Guidelines for appropriate use of antibiotics in developing countries need updating.

* Corresponding author. Mailing address: Laboratori de Microbiologia, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain. Phone: 34.93.2275522. Fax: 34.93.2275454. E-mail: vila{at}medicina.ub.es.

Antimicrobial Agents and Chemotherapy, December 1999, p. 3022-3024, Vol. 43, No. 12
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Ochoa, T. J., Ruiz, J., Molina, M., Del Valle, L. J., Vargas, M., Gil, A. I., Ecker, L., Barletta, F., Hall, E., Cleary, T. G., Lanata, C. F. (2009). High Frequency of Antimicrobial Drug Resistance of Diarrheagenic Escherichia coli in Infants in Peru. Am J Trop Med Hyg 81: 296-301 [Abstract] [Full Text]  
  • Nwaneshiudu, A. I., Mucci, T., Pickard, D. J., Okeke, I. N. (2007). A Second Large Plasmid Encodes Conjugative Transfer and Antimicrobial Resistance in O119:H2 and Some Typical O111 Enteropathogenic Escherichia coli Strains. J. Bacteriol. 189: 6074-6079 [Abstract] [Full Text]  
  • Joo, L. M., Macfarlane-Smith, L. R., Okeke, I. N. (2007). Error-Prone DNA Repair System in Enteroaggregative Escherichia coli Identified by Subtractive Hybridization. J. Bacteriol. 189: 3793-3803 [Abstract] [Full Text]  
  • Frank, T., Gautier, V., Talarmin, A., Bercion, R., Arlet, G. (2007). Characterization of sulphonamide resistance genes and class 1 integron gene cassettes in Enterobacteriaceae, Central African Republic (CAR). J Antimicrob Chemother 59: 742-745 [Abstract] [Full Text]  
  • MANDOMANDO, I. M., MACETE, E. V., RUIZ, J., SANZ, S., ABACASSAMO, F., VALLES, X., SACARLAL, J., NAVIA, M. M., VILA, J., ALONSO, P. L., GASCON, J. (2007). ETIOLOGY OF DIARRHEA IN CHILDREN YOUNGER THAN 5 YEARS OF AGE ADMITTED IN A RURAL HOSPITAL OF SOUTHERN MOZAMBIQUE. Am J Trop Med Hyg 76: 522-527 [Abstract] [Full Text]  
  • Nguyen, T. V., Le, P. V., Le, C. H., Weintraub, A. (2005). Antibiotic Resistance in Diarrheagenic Escherichia coli and Shigella Strains Isolated from Children in Hanoi, Vietnam. Antimicrob. Agents Chemother. 49: 816-819 [Abstract] [Full Text]  
  • VILA, J., VARGAS, M., RUIZ, J., ESPASA, M., PUJOL, M., CORACHAN, M., ANTA, M. T. J. D., GASCON, J. (2001). Susceptibility patterns of enteroaggregative Escherichia coli associated with traveller's diarrhoea: emergence of quinolone resistance. J Med Microbiol 50: 996-1000 [Abstract] [Full Text]  
  • Sierra, J. M., Navia, M. M., Vargas, M., Urassa, H., Schellemberg, D., Gascon, J., Vila, J., Ruiz, J. (2001). In vitro activity of rifaximin against bacterial enteropathogens causing diarrhoea in children under 5 years of age in Ifakara, Tanzania. J Antimicrob Chemother 47: 904-905 [Full Text]  
  • Sierra, J. M., Ruiz, J., Navia, M. M., Vargas, M., Gascon, J., Vila, J. (2001). In Vitro Activity of Rifaximin against Enteropathogens Producing Traveler's Diarrhea. Antimicrob. Agents Chemother. 45: 643-644 [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»