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Antimicrobial Agents and Chemotherapy, April 1999, p. 944-946, Vol. 43, No. 4
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Presence of mefA and mefE Genes in Streptococcus agalactiae

C. Arpin,* H. Daube, F. Tessier, and C. Quentin

Laboratoire de Microbiologie, Université Victor Segalen Bordeaux 2, 33076 Bordeaux Cedex, France

Received 9 November 1998/Returned for modification 9 December 1998/Accepted 14 January 1999

Eighteen unrelated clinical isolates of Streptococcus agalactiae with the M phenotype harbored an mef gene. DNA sequencing showed that one of nine strains contained mefA (producing one amino acid substitution), whereas the remaining eight carried mefE (identity, 100%). Restriction analysis of PCR products indicated that the nine other strains also contained mefE.


* Corresponding author. Mailing address: Laboratoire de Microbiologie, Université Victor Segalen Bordeaux 2, 146, rue Léo Saignat, 33076 Bordeaux Cedex, France. Phone: (33) 5-57-57-10-75. Fax: (33) 5-56-90-90-72. E-mail: corinne.arpin{at}bacterio.u-bordeaux2.fr.


Antimicrobial Agents and Chemotherapy, April 1999, p. 944-946, Vol. 43, No. 4
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.



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