This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Goldstein, E. J. C.
Right arrow Articles by Merriam, C. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Goldstein, E. J. C.
Right arrow Articles by Merriam, C. V.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, June 1999, p. 1469-1474, Vol. 43, No. 6
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Linezolid Activity Compared to Those of Selected Macrolides and Other Agents against Aerobic and Anaerobic Pathogens Isolated from Soft Tissue Bite Infections in Humans

Ellie J. C. Goldstein,1,2,* Diane M. Citron,1 and C. Vreni Merriam1

R. M. Alden Research Laboratory, Santa Monica-UCLA Medical Center, Santa Monica, California 90404,1 and UCLA School of Medicine, Los Angeles, California 900242

Received 23 October 1998/Returned for modification 21 February 1999/Accepted 14 March 1999

Linezolid was tested against 420 aerobes and anaerobes, including 148 Pasteurella isolates, by an agar dilution method. Linezolid was active against all Pasteurella multocida subsp. multocida and P. multocida subsp. septica isolates and most Pasteurella canis, Pasteurella dagmatis, and Pasteurella stomatis isolates. The MIC was <= 2 µg/ml for staphylococci, streptococci, EF-4b, Weeksella zoohelcum, Fusobacterium nucleatum, other fusobacteria, Porphyromonas spp., Prevotella spp., peptostreptococci, and almost all Bacteroides tectum isolates.

* Corresponding author. Mailing address: 2021 Santa Monica Blvd., Suite 640E, Santa Monica, CA 90404. Phone: (310) 315-1511. Fax: (310) 315-3662. E-mail: EJCGMD{at}aol.com.

Antimicrobial Agents and Chemotherapy, June 1999, p. 1469-1474, Vol. 43, No. 6
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Daeschlein, G., Hoehne, C., Assadian, O., Daxboeck, F., Meinl, C., Kramer, A., Kekule, A.S. (2006). In vitro activity of linezolid against clinical isolates of Fusobacterium spp.. J Antimicrob Chemother 58: 789-793 [Abstract] [Full Text]  
  • Jones, R. N., Ross, J. E., Fritsche, T. R., Sader, H. S. (2006). Oxazolidinone susceptibility patterns in 2004: report from the Zyvox(R) Annual Appraisal of Potency and Spectrum (ZAAPS) Program assessing isolates from 16 nations. J Antimicrob Chemother 57: 279-287 [Abstract] [Full Text]  
  • Shukla, S. K., Paustian, D. L., Stockwell, P. J., Morey, R. E., Jordan, J. G., Levett, P. N., Frank, D. N., Reed, K. D. (2004). Isolation of a Fastidious Bergeyella Species Associated with Cellulitis after a Cat Bite and a Phylogenetic Comparison with Bergeyella zoohelcum Strains. J. Clin. Microbiol. 42: 290-293 [Abstract] [Full Text]  
  • Sweeney, M. T., Zurenko, G. E. (2003). In Vitro Activities of Linezolid Combined with Other Antimicrobial Agents against Staphylococci, Enterococci, Pneumococci, and Selected Gram-Negative Organisms. Antimicrob. Agents Chemother. 47: 1902-1906 [Abstract] [Full Text]  
  • Ednie, L. M., Rattan, A., Jacobs, M. R., Appelbaum, P. C. (2003). Antianaerobe Activity of RBX 7644 (Ranbezolid), a New Oxazolidinone, Compared with Those of Eight Other Agents. Antimicrob. Agents Chemother. 47: 1143-1147 [Abstract] [Full Text]  
  • Gunderson, B. W., Ibrahim, K. H., Peloquin, C. A., Hovde, L. B., Rotschafer, J. C. (2003). Comparison of Linezolid Activities under Aerobic and Anaerobic Conditions against Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus faecium. Antimicrob. Agents Chemother. 47: 398-399 [Abstract] [Full Text]  
  • Ednie, L. M., Jacobs, M. R., Appelbaum, P. C. (2002). Anti-anaerobic activity of AZD2563, a new oxazolidinone, compared with eight other agents. J Antimicrob Chemother 50: 101-105 [Abstract] [Full Text]  
  • Tyrrell, K. L., Citron, D. M., Jenkins, J. R., Goldstein, E. J. C. (2002). Periodontal Bacteria in Rabbit Mandibular and Maxillary Abscesses. J. Clin. Microbiol. 40: 1044-1047 [Abstract] [Full Text]  
  • Drago, L., De Vecchi, E., Valli, M., Nicola, L., Gismondo, M. R. (2002). Effect of Linezolid in Comparison with That of Vancomycin on Glycocalix Production: In Vitro Study. Antimicrob. Agents Chemother. 46: 598-599 [Full Text]  
  • Tubau, F., Fernandez-Roblas, R., Linares, J., Martin, R., Soriano, F. (2001). In vitro activity of linezolid and 11 other antimicrobials against 566 clinical isolates and comparison between NCCLS microdilution and Etest methods. J Antimicrob Chemother 47: 675-680 [Abstract] [Full Text]  
  • Brown-Elliott, B. A., Ward, S. C., Crist, C. J., Mann, L. B., Wilson, R. W., Wallace, R. J. Jr. (2001). In Vitro Activities of Linezolid against Multiple Nocardia Species. Antimicrob. Agents Chemother. 45: 1295-1297 [Abstract] [Full Text]  
  • Hirschl, A. M., Apfalter, P., Makristathis, A., Rotter, M. L., Wimmer, M. (2000). In Vitro Activities of Linezolid Alone and in Combination with Amoxicillin, Clarithromycin, and Metronidazole against Helicobacter pylori. Antimicrob. Agents Chemother. 44: 1977-1979 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»