Antimicrobial Agents and Chemotherapy, June 1999, p. 1475-1479, Vol. 43, No. 6
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
R. M. Alden Research Laboratory, Santa Monica-UCLA Medical Center, Santa Monica, California 90404,1 and UCLA School of Medicine, Los Angeles, California 900242
Received 23 October 1998/Returned for modification 21 February 1999/Accepted 14 March 1999
The activity of gatifloxacin against 308 aerobes and 112 anaerobes
isolated from bite wound infections was studied. Gatifloxacin was
active at
0.016 µg/ml against all 148 Pasteurella
isolates (eight species and three subspecies) tested and all other
aerobes tested, including Actinobacillus-Haemophilus spp.,
Eikenella corrodens, Neisseria weaveri,
Weeksella zoohelcum, staphylococci, and streptococci. Fusobacteria were sometimes resistant. Gatifloxacin MICs at which 90%
of the isolates were inhibited were 0.125 µg/ml against
Bacteroides tectum and Prevotella spp., 0.25 µg/ml against Porphyromonas spp., and 0.5 µg/ml against peptostreptococci.
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