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Antimicrobial Agents and Chemotherapy, July 1999, p. 1803-1804, Vol. 43, No. 7
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Sensitivity of Amoxicillin-Resistant Helicobacter pylori to Other Penicillins

Maria P. Dore,1,* David Y. Graham,1 Antonia R. Sepulveda,1 Giuseppe Realdi,2 and Michael S. Osato1

Department of Medicine, VA Medical Center, and Baylor College of Medicine, Houston, Texas 77030,1 and Department of Internal Medicine, University of Sassari, Sassari, Italy 071002

Received 24 November 1998/Returned for modification 8 March 1999/Accepted 7 May 1999

The sensitivities to penicillins and to a penicillin and beta -lactamase inhibitor combination agent were determined for Helicobacter pylori strains that were sensitive, moderately resistant, or highly resistant to amoxicillin. All strains were resistant to nafcillin and oxacillin. Moderately resistant strains showed an intermediate zone of inhibition to ticarcillin, mezlocillin, piperacillin, and amoxicillin-clavulanic acid. High-level resistance was associated with the smallest zone size for all penicillins tested.

* Corresponding author. Mailing address: Department of Medicine, VA Medical Center (111D), 2002 Holcombe Blvd., Houston, TX 77030. Phone: (713) 794-7233. Fax: (713) 795-4471. E-mail: mariap{at}bcm.tmc.edu.

Antimicrobial Agents and Chemotherapy, July 1999, p. 1803-1804, Vol. 43, No. 7
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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  • DeLoney, C. R., Schiller, N. L. (2000). Characterization of an In Vitro-Selected Amoxicillin-Resistant Strain of Helicobacter pylori. Antimicrob. Agents Chemother. 44: 3368-3373 [Abstract] [Full Text]  


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