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Antimicrobial Agents and Chemotherapy, August 1999, p. 2069-2073, Vol. 43, No. 8
Service de Bactériologie,
Received 23 December 1998/Returned for modification 12 April
1999/Accepted 29 May 1999
Four species of members of the family
Enterobacteriaceae harboring extended-spectrum
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
TEM-24 Produced by Four Different Species of
Enterobacteriaceae, Including Providencia
rettgeri, in a Single Patient
-lactamase (ESBL) were recovered in a single patient hospitalized in
an intensive care unit. Among these isolates, we describe for the first
time an ESBL-producing Providencia rettgeri strain.
Bacteria from the same species were shown to be genetically related by
pulsed-field gel electrophoresis analysis. These strains produced the
same TEM derivative ESBL, characterized as TEM-24. This enzyme had the
peculiarity of being encoded by a large conjugative plasmid of 180 kb,
never previously described for such an ESBL.
*
Corresponding author. Mailing address: Laboratoire de
Bactériologie, Hôpital Arnaud de Villeneuve, 371, Avenue du
Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France. Phone: 33 4 67 33 58 86. Fax: 33 4 67 33 58 93. E-mail:
h=marchandin{at}chu-montpellier.fr.
Antimicrobial Agents and Chemotherapy, August 1999, p. 2069-2073, Vol. 43, No. 8
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
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