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Antimicrobial Agents and Chemotherapy, September 1999, p. 2320-2322, Vol. 43, No. 9
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Activities of New Antimicrobial Agents (Trovafloxacin, Moxifloxacin, Sanfetrinem, and Quinupristin-Dalfopristin) against Bacteroides fragilis Group: Comparison with the Activities of 14 Other Agents

Carmen Betriu,* María Gómez, M. Luisa Palau, Ana Sánchez, and Juan J. Picazo

Servicio de Microbiología Clínica, Hospital Clínico San Carlos, 28040 Madrid, Spain

Received 11 March 1999/Returned for modification 13 May 1999/Accepted 29 June 1999

The antimicrobial activities of trovafloxacin, moxifloxacin, sanfetrinem, quinupristin-dalfopristin, and 14 other antimicrobial agents against 218 Bacteroides fragilis group strains were determined. A group of 10 imipenem-resistant strains were also tested. Imipenem, meropenem, and sanfetrinem had the lowest MICs of all of the beta -lactams. Quinupristin-dalfopristin inhibited all of the strains at 2 µg/ml. Overall, the MICs of trovafloxacin and moxifloxacin for 90% of the strains tested were 1 and 2 µg/ml, respectively.

* Corresponding author. Mailing address: Servicio de Microbiología Clínica, Hospital Clínico San Carlos, Plaza Cristo Rey s/n, 28040 Madrid, Spain. Phone: 341 3303486. Fax: 341 3303478. E-mail: cbetriu{at}efd.net.

Antimicrobial Agents and Chemotherapy, September 1999, p. 2320-2322, Vol. 43, No. 9
0066-4804/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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