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Antimicrobial Agents and Chemotherapy, January 2000, p. 167-168, Vol. 44, No. 1
0066-4804/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Successful Treatment with Nitazoxanide of Enterocytozoon bieneusi Microsporidiosis in a Patient with AIDS

Alain Bicart-Sée,1,* Patrice Massip,1 Marie-Denise Linas,2 and Annick Datry3

Department of Infectious and Tropical Diseases, Purpan Hospital,1 and Parasitology-Mycology Laboratory, Rangueil Hospital,2 Toulouse, and Parasitology-Mycology Laboratory, Pitie-Salpetriere Hospital, Paris,3 France

Received 11 March 1999/Returned for modification 23 August 1999/Accepted 13 October 1999

A patient with AIDS and chronic diarrhea caused by Enterocytozoon bieneusi was successfully treated with nitazoxanide, producing a complete clinical and parasitological response, while off of antiviral therapy. This suggests that nitazoxanide may be effective in treating microsporidiosis caused by E. bieneusi, a disease for which there is no established treatment.

* Corresponding author. Mailing address: Service des Maladies Infectieuses, Hôpital Purpan, 31059 Toulouse Cedex, France. Phone: 33 561 77 20 92. Fax: 33 561 77 34 73. E-mail: bicart{at}club-internet.fr.

Antimicrobial Agents and Chemotherapy, January 2000, p. 167-168, Vol. 44, No. 1
0066-4804/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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