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Antimicrobial Agents and Chemotherapy, January 2000, p. 181-182, Vol. 44, No. 1
0066-4804/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

In Vitro Susceptibilities of Rapidly Growing Mycobacteria to Telithromycin (HMR 3647) and Seven Other Antimicrobials

Ricardo Fernández-Roblas,1 Jaime Esteban,1 Froilán Cabria,1 Juan Carlos López,1 Maria Soledad Jiménez,2 and Francisco Soriano1,*

Department of Medical Microbiology, Fundación Jiménez Díaz,1 and Centro Nacional de Microbiología, Majadahonda,2 Madrid, Spain

Received 14 July 1999/Returned for modification 23 August 1999/Accepted 22 October 1999

The antimicrobial activities of telithromycin (HMR 3647) and seven other antimicrobials against 94 strains of rapidly growing mycobacteria were determined. Telithromycin at a concentration of 1 µg/ml inhibited Mycobacterium peregrinum (100%), Mycobacterium chelonae (80%), Mycobacterium abscessus-Mycobacterium mucogenicum (44.4%), and Mycobacterium fortuitum (2.1%). All or most strains of M. peregrinum, M. fortuitum, and M. mucogenicum were inhibited by 2 µg of quinolones per ml.

* Corresponding author. Mailing address: Department of Medical Microbiology, Fundación Jiménez Díaz, Avenida de Reyes Católicos 2, 28040 Madrid, Spain. Phone: 34-1-544.73.87. Fax: 34-1-549.47.64. E-mail: fsoriano{at}microb.net.

Antimicrobial Agents and Chemotherapy, January 2000, p. 181-182, Vol. 44, No. 1
0066-4804/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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