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Antimicrobial Agents and Chemotherapy, January 2000, p. 210-212, Vol. 44, No. 1
0066-4804/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Complete Sequence of a beta -Lactamase-Encoding Plasmid in Neisseria meningitidis

Anders Bäckman,1,* Paula Orvelid,1 Julio A. Vazquez,2 Ola Sköld,3 and Per Olcén1

Department of Clinical Microbiology and Immunology, Örebro Medical Center Hospital, SE-701 85 Örebro,1 and Department of Pharmaceutical Bioscience, Biomedical Centre, Uppsala University, SE-751 23 Uppsala,3 Sweden, and Servicio de Bacteriologíca, Centro Nacional de Microbiologíca, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain2

Received 25 February 1999/Returned for modification 4 June 1999/Accepted 6 October 1999

Identical beta -lactamase-encoding (TEM-1) plasmids were found in two different clinical Neisseria meningitidis strains. They were completely sequenced (5,597 bp) and designated pAB6. The plasmid is almost identical to Neisseria gonorrhoeae plasmid pJD5 (5,599 kb) and may have been picked up from a gonococcus in vivo.

* Corresponding author. Mailing address: Department of Clinical Microbiology and Immunology, Örebro Medical Center Hospital, SE-701 85 Örebro, Sweden. Phone: 4619151520. Fax: 4619127416. E-mail: anders.backman{at}orebroll.se.

Antimicrobial Agents and Chemotherapy, January 2000, p. 210-212, Vol. 44, No. 1
0066-4804/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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