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Antimicrobial Agents and Chemotherapy, January 2000, p. 213-216, Vol. 44, No. 1
0066-4804/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Production of a TEM-24 Plasmid-Mediated Extended-Spectrum beta -Lactamase by a Clinical Isolate of Pseudomonas aeruginosa

Helene Marchandin,1,* Helene Jean-Pierre,1 Christophe De Champs,2 Danielle Sirot,2 Helene Darbas,1 Pierre Francois Perigault,3 and Christian Carriere1

Service de Bactériologie, Hôpital Arnaud de Villeneuve, 34295 Montpellier Cedex 5,1 Service de Bactériologie, Faculté de Médecine et de Pharmacie, 63001 Clermont Ferrand,2 and Département d'Anesthésie et de Réanimation DARB, Hôpital Saint Eloi, 34000 Montpellier,3 France

Received 31 March 1999/Returned for modification 25 July 1999/Accepted 21 October 1999

Several Pseudomonas aeruginosa strains, including one urinary isolate producing an extended-spectrum beta -lactamase TEM-24, were isolated from a long-term-hospitalized woman. Three TEM-24-producing enterobacterial species (Enterobacter aerogenes, Escherichia coli, and Proteus mirabilis) were isolated from the same patient. TEM-24 and the resistance markers for aminoglycosides, chloramphenicol, and sulfonamide were encoded by a 180-kb plasmid transferred by conjugation into E. coli HB101.


* Corresponding author. Mailing address: Laboratoire de Bactériologie, Hôpital Arnaud de Villeneuve, 371, Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France. Phone: 33 4 67 33 58 86. Fax: 33 4 67 33 58 93. E-mail: h-marchandin{at}chu-montpellier.fr.


Antimicrobial Agents and Chemotherapy, January 2000, p. 213-216, Vol. 44, No. 1
0066-4804/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.



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