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Antimicrobial Agents and Chemotherapy, November 2000, p. 3220-3223, Vol. 44, No. 11
Service de Bactériologie-Virologie,
Hôpital de Bicêtre, Assistance Publique/Hôpitaux de
Paris, Faculté de Médecine Paris-Sud, 94275 Le
Kremlin-Bicêtre, France
Received 28 February 2000/Returned for modification 16 June
2000/Accepted 18 August 2000
Ten unrelated Hafnia alvei clinical isolates were
grouped according to either their low-level and inducible
cephalosporinase production or their high-level and constitutive
cephalosporinase production phenotype. Their AmpC sequences shared 85 to 100% amino acid identity. The immediate genetic environment of
ampC genes was conserved in H. alvei isolates
but was different from that found in other ampC-possessing
enterobacterial species.
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
Heterogeneity of AmpC Cephalosporinases of
Hafnia alvei Clinical Isolates Expressing Inducible or
Constitutive Ceftazidime Resistance Phenotypes
*
Corresponding author. Mailing address: Service de
Bactériologie-Virologie, Hôpital de Bicêtre, 78 rue
du Général Leclerc, 94275 Le Kremlin-Bicêtre Cedex,
France. Phone: 33 1 45 21 36 32. Fax: 33 1 45 21 63 40. E-mail:
nordmann.patrice{at}bct.ap-hop-paris.fr.
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