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Antimicrobial Agents and Chemotherapy, February 2000, p. 411-413, Vol. 44, No. 2
Department of Microbiology, Monash
University, Clayton, Victoria 3800, Australia
Received 26 April 1999/Returned for modification 4 May
1999/Accepted 29 October 1999
The ErmB macrolide-lincosamide-streptogramin B (MLS) resistance
determinant from Clostridium difficile 630 contains two
copies of an erm(B) gene, separated by a 1.34-kb direct
repeat also found in an Erm(B) determinant from Clostridium
perfringens. In addition, both erm(B) genes are
flanked by variants of the direct repeat sequence. This genetic
arrangement is novel for an ErmB MLS resistance determinant.
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
The Macrolide-Lincosamide-Streptogramin B
Resistance Determinant from Clostridium difficile 630 Contains Two erm(B) Genes
*
Corresponding author. Mailing address: Department of
Microbiology, Monash University, Clayton, Victoria 3800, Australia.
Phone: 61-3-9905-4825. Fax: 61-3-9905-4811. E-mail:
Julian.Rood{at}med.monash.edu.au.
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