AAC
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bou, G.
Right arrow Articles by Martínez-Beltrán, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bou, G.
Right arrow Articles by Martínez-Beltrán, J.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, February 2000, p. 428-432, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Cloning, Nucleotide Sequencing, and Analysis of the Gene Encoding an AmpC beta -Lactamase in Acinetobacter baumannii

Germán Bou* and Jesús Martínez-Beltrán

Servicio de Microbiología, Hospital Ramón y Cajal, 28034 Madrid, Spain

Received 13 January 1999/Returned for modification 29 August 1999/Accepted 5 November 1999

A clinical strain of Acinetobacter baumannii (strain Ab RYC 52763/97) that was isolated during an outbreak in our hospital and that was resistant to all beta -lactam antibiotics tested produced three beta -lactamases: a TEM-1-type (pI, 5.4) plasmid-mediated beta -lactamase, a chromosomally mediated OXA-derived (pI, 9.0) beta -lactamase, and a presumptive chromosomal cephalosporinase (pI, 9.4). The nucleotide sequence of the chromosomal cephalosporinase gene shows for the first time the gene encoding an AmpC beta -lactamase in A. baumannii. In addition, we report here the biochemical properties of this A. baumannii AmpC beta -lactamase.

* Corresponding author. Present address: Department of Immunology and Division of Infectious Diseases, Mayo Clinic, 200 First St. SW, Guggenheim 516, Rochester, MN 55905. Phone: (507) 284-9504. Fax: (507) 284-3757. E-mail: germanbou{at}mailcity.com.

Antimicrobial Agents and Chemotherapy, February 2000, p. 428-432, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Clin. Vaccine Immunol. Clin. Microbiol. Rev.
J. Clin. Microbiol. ALL ASM JOURNALS

Copyright © 2000 by the American Society for Microbiology. All rights reserved.