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Antimicrobial Agents and Chemotherapy, February 2000, p. 456-457, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Resistance to Mercury and Antimicrobial Agents in Streptococcus mutans Isolates from Human Subjects in Relation to Exposure to Dental Amalgam Fillings

Jorma Leistevuo,1,2,* Helinä Järvinen,1 Monica Österblad,1 Tiina Leistevuo,1,3 Pentti Huovinen,1 and Jorma Tenovuo2

National Public Health Institute, Antimicrobial Research Laboratory,1 and Department of Physical Medicine and Rehabilitation, Turku University Hospital,3 FIN-20521 Turku, and Institute of Dentistry, Turku University, FIN-20520 Turku,2 Finland

Received 7 May 1999/Returned for modification 10 August 1999/Accepted 13 November 1999

Resistance to cefuroxime, penicillin, tetracycline, and mercury is reported for 839 Streptococcus mutans isolates from 209 human study subjects. The MICs of these drugs did not differ for isolates from one dental amalgam group and two nonamalgam subsets: a group with no known exposure to amalgam and a group whose members had their amalgam fillings removed.

* Corresponding author. Mailing address: National Public Health Institute, Antimicrobial Research Laboratory, P.O. Box 57, FIN-20521 Turku, Finland. Phone: 358-2-2519-255. Fax: 358-2-2519-254.

Antimicrobial Agents and Chemotherapy, February 2000, p. 456-457, Vol. 44, No. 2
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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