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Antimicrobial Agents and Chemotherapy, March 2000, p. 775-777, Vol. 44, No. 3
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Occurrence of the New Tetracycline Resistance Gene tet(W) in Bacteria from the Human Gut

Karen P. Scott,* Claire M. Melville, Teresa M. Barbosa,dagger and Harry J. Flint

Rowett Research Institute, Bucksburn, Aberdeen, AB21 9SB, United Kingdom

Received 9 August 1999/Returned for modification 2 November 1999/Accepted 16 December 1999

Members of our group recently identified a new tetracycline resistance gene, tet(W), in three genera of rumen obligate anaerobes. Here, we show that tet(W) is also present in bacteria isolated from human feces. The tet(W) genes found in human Fusobacterium prausnitzii and Bifidobacterium longum isolates were more than 99.9% identical to those from a rumen isolate of Butyrivibrio fibrisolvens.

* Corresponding author. Mailing address: Rowett Research Institute, Greenburn Rd., Bucksburn, Aberdeen, AB21 9SB, United Kingdom. Phone: 44 (0) 1224 712751. Fax: 44 (0) 1224 716687. E-mail: k.scott{at}rri.sari.ac.uk.

dagger Present address: Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111.

Antimicrobial Agents and Chemotherapy, March 2000, p. 775-777, Vol. 44, No. 3
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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